Boswellin®
The book titled Boswellin® The Anti-inflammatory Phytonutrient, written by M. Majeed et al., was published in 1996 by Nutriscience publishers, Inc. When this book was published, much of the patent literature concerning Boswellia serrata, its pharmacologically active constituents specifically known as β-boswellic acids, and similar species (B. carterii) was unavailable.
Research
Boswellic acids have been found to inhibit 5-lipoxygenase (5-LO) , as well as, human leukocyte elastase (HLE), the serine protease produced and released by polymorphonuclear leukocytes (PMNLs)
The presence of a specific AKBA-binding site on 5-lipooxygense (5-LO) that is distinct from the arachidonate substrate-binding site was determined using photoaffinity labeling.
Leukotrienes are fatty acids which are formed from arachidonic acid by an enzyme called 5-lipoxygenase(5-LO)
BOSWELLIN®
THE ANTI-INFLAMMATORY PHYTONUTRIENT